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GraphPad Software Inc
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GraphPad Software Inc
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STATA Corporation
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Malvern Panalytical
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STATA Corporation
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Image Search Results
Journal: iScience
Article Title: Thyroid hormone treatment counteracts cellular phenotypical remodeling in diabetic organs
doi: 10.1016/j.isci.2023.107826
Figure Lengend Snippet: Treatment with T3 counteracts pathological growth in diabetes- and glucose-injured podocytes and cardiomyocytes and maintains cardiomyocytes cytoarchitecture (A and B) Representative images of Glepp1 (A) and WT1 (B) staining in kidney serial sections of lean and diabetic animals. Quantification of individual podocyte volume and WT1-positive podocytes in lean and ZDF rats (A and B, right). (C) Quantification of Feret’s diameter in cardiomyocytes. (D and E) Evaluation of DNA content in glomerular cells (D) and cardiomyocytes (E) of control and diabetic animals. (F) Representative images of 3D reconstructed kidney (top) and heart (bottom) tissue sections. Tissues were stained with rhodamine-labeled WGA lectin. (G–I) Quantification of cell area (G, H) and axis ratio (I) in control, glucose-injured, and T3-treated human podocytes (G) and cardiomyocytes (H, I). For quantification, representative images were randomly taken from different areas of cell culture. At least 91 cells from each group were analyzed from n = 3 independent experiments (G–I). Data are expressed as mean ± SEM, one-way ANOVA corrected with Tukey’s post hoc test. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗∗p < 0.0001. n = 5–6 animals per group. Scale bars, 20 μm (A, B), 40 μm (F).
Article Snippet:
Techniques: Staining, Control, Labeling, Cell Culture
Journal: iScience
Article Title: Thyroid hormone treatment counteracts cellular phenotypical remodeling in diabetic organs
doi: 10.1016/j.isci.2023.107826
Figure Lengend Snippet:
Article Snippet:
Techniques: Recombinant, Plasmid Preparation, Membrane, Enzyme-linked Immunosorbent Assay, DC Protein Assay, Software